Sublocade™ (buprenorphine, extended-release)

Sublocade

What is Sublocade?

Sublocade ™ is the trademark for a new monthly injection of buprenorphine (the active drug in Suboxone). The FDA approved this injectable extended-release buprenorphine drug, in 2017, as a schedule III-controlled substance for the treatment of moderate to severe OUD (Opioid Use Disorder). Before Sublocade ™ was introduced, buprenorphine drugs were typically available in daily oral form and absorbed through the lining of the mouth.  Now the injection is given subcutaneously in your belly.

The initial price for Sublocade™ was $1580 per injection, monthly. This cost does not include additional pharmacy charges and the doctor/provider administering the medication. There are currently no competitors or generic forms of Sublocade. The current price for this drug depends on your insurance plan and your location.

How Does It Work?

Because Sublocade™ is also an opioid, the drug acts on the same receptor sites as other drugs in the same class, such as morphine and heroin. Furthermore, Sublocade™ can also be abused — just like any other opioid, it stimulates the receptors — and given the potential for abuse, the drug has tight controls and legal restrictions.

One of the most significant benefits of this drug is that it does have a ceiling. In other words, its effects do not increase after a specific dose, which makes the drug less likely to be abused and, consequently, it can prevent an overdose from occurring.

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Dosage

The recommended dose following induction and adjustment with transmucosal buprenorphine is 300mg subcutaneously (SC) for the first two months, followed by a maintenance dose of 100mg SC monthly. — The maintenance dose may be increased to 300 mg for those who do not demonstrate a satisfactory clinical response. There is no established duration of treatment.

** Although the information above describes the most commonly used dosages, your doctor is the one that should determine what amount suits your specific health needs.

Side Effects

As with any opioid drug, Sublocade can cause many mild to serious side effects. The following lists contain some of the main effects that can occur. It is important to remember that the lists do not include all possible side effects.

For a more complete list of the possible Sublocade side effects, please talk with your doctor or pharmacist.

Some of the most common effects are:

  • Itchiness, redness or tenderness at the injection site
  • Constipation
  • Headache
  • Nausea or vomiting
  • Fatigue
  • Dizziness, especially when getting up from sitting or lying down
  • Physical dependence which can lead to risky behavior and drug abuse

* Physical dependence can lead to weeks to months of withdrawal symptoms after you stop taking Sublocade.

Serious Side Effects

Although serious side effects are not common, they can occur. If you have doubts about what you are feeling, call your doctor right away. If your symptoms feel life-threatening or if you think you have a medical emergency, call 911.

Serious side effects can include the following:

  • allergic reactions
  • difficulty breathing
  • liver damage
  • adrenal gland issues

Sublocade™ also can lead to some more severe side effects such as shallow or interrupted breathing, coma, and even death. Typically, these severe side effects are in cases when Sublocade™ is abused, combined with other substances, or administered intravenously.

Sublocade Withdrawal

As with any other buprenorphine drug, you can become physically dependent on Sublocade, which can lead to withdrawal after discontinuing treatment.

If you are suffering from Sublocade withdrawal, you should seek medical assistance. Symptoms of withdrawal may include:

  • goosebumps
  • muscle aches
  • shaking
  • anxiety
  • sweating
  • feeling hot or cold
  • runny nose
  • watery eyes
  • sleeplessness
  • diarrhea
  • vomiting

It’s imperative to discuss with your doctor the best way to discontinue any form of opioid use. When detox is managed medically, withdrawal symptoms are significantly reduced.

More Drugs to Solve a Drug Epidemic

The consequences of the opioid epidemic, in our society, have been tragic in so many ways. It continues to cause tremendous suffering due to overdoses, orphan children, and broken families all across the country.

People start scrambling to find instant solutions to a problem that has been growing for years — a problem that is mostly and the consequence of an untreated mental health condition. So, what do we do? Do we focus on the cause or remedy the symptoms?

It doesn’t matter how people initially start using opioid drugs — the outcome is the same. Having to seek drugs by prescription or at the streets to self-medicate distress (regardless of physical, emotional, or both) is horrible and unfair imprisonment. One that does not usually go away without professional help. It is not enough to do more; we need to do better. Let’s provide effective treatment that leads to long term solutions.

WAISMANN DETOX for Sublocade

Waismann Method is a safer, faster, and much more comfortable way to start your life journey, free from opioid drugs.

If you or a loved one are currently suffering from opioid addiction, remember:

  1. You are not alone
  2. Opioid addiction is NOT a sign of weakness, but a consequence of an untreated condition
  3. Opioid dependence (including those dependencies on buprenorphine) is a treatable condition
  4. Inpatient medically managed detox is a much more effective and a safer option to come off opioid drugs.
  5. Opioid detox treatment can take only a few days, which creates minimal disruption to your life.
  6. In most cases, outpatient individual mental health care can be hugely successful when combined with a healthy and productive environment.
  7. You won’t need to handle the suffering and discomfort that causes most people to relapse when they try to overcome withdrawal alone.

The WAISMANN DETOX® has been providing detox and a tailored treatment plan for patients who have an opioid addiction. Our goal is to offer an opioid-free solution, while minimizing withdrawal symptoms and reduce drug cravings as fast, as safe and as comfortable as possible. Depending on your unique health needs, you can confidentially complete treatment in as little as 5-10 days. Our detox success rate is nearly 100%.

Contact one of the caring, professional representatives to learn more about the best treatment option for you. Ask us about rapid detox, medically assisted opioid detox, and aftercare treatment options. Let us help you become completely opioid-free, with a more comfortable, quicker, safer detox.

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