The 7 Most Common Percocet Questions Answered

Close up photo of a doctor holding a book on opioid management - concept of most common Percocet questions answered

Percocet, a potent pain reliever often prescribed following surgery or injury, has various implications for health and well-being. Due to its opioid component, it raises several questions about its use, effects, and risks. This blog post aims to address the most common inquiries about Percocet, providing you with reliable information to ensure safe usage.

1. What is Percocet?

Percocet combines oxycodone, a powerful opioid painkiller, with acetaminophen, a non-opioid pain reliever used to enhance oxycodone’s effects. This medication is prescribed to manage moderate to severe pain but comes with strict guidelines due to its high potential for addiction and dependency.

2. Is Percocet an Opiate?

Yes, Percocet is classified as an opioid because it contains oxycodone, which is derived from the opium poppy. It acts on the central nervous system to relieve pain but also poses risks of abuse and addiction, leading to it being highly regulated.

3. Does Percocet Contain Codeine?

No, Percocet does not contain codeine. While both codeine and oxycodone are opioids, Percocet specifically uses oxycodone as its opioid component combined with acetaminophen to manage pain more effectively and reduce fever.

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4. How Long Does Percocet Stay in Your System?

Percocet’s detectability in the body depends on several factors, including metabolism, body mass, age, and liver function. Generally, Percocet can be detected in urine for up to 48 hours after the last dose. It can be found in blood tests for about 24 hours, in saliva for 1-4 days, and in hair for up to 90 days. Understanding these timelines is important for those undergoing drug testing or managing withdrawal.

5. Can You Take Percocet and Ibuprofen Together?

Yes, it is generally safe to take Percocet and ibuprofen together. This combination can be effective in managing pain, as ibuprofen reduces inflammation while Percocet blocks pain signals to the brain. However, always consult with a healthcare provider before combining medications to ensure safety and effectiveness.

6. Is Percocet Stronger than Hydrocodone?

Percocet and hydrocodone are both powerful pain relievers that contain opioid components. The strength and effectiveness can vary depending on the individual’s pain tolerance and medical condition. Percocet is often perceived to be slightly stronger due to oxycodone’s potency compared to hydrocodone.

7. What Are the Risks of Percocet Addiction?

The risk of addiction to Percocet is significant due to its oxycodone content. Prolonged or unsupervised use can lead to physical dependence and addiction. Symptoms of addiction might include uncontrollable cravings, inability to reduce usage despite harmful consequences, and withdrawal symptoms when not using the drug. It is crucial to follow a doctor’s prescription and guidelines to minimize these risks.


Understanding Percocet is crucial for those prescribed this medication. By addressing these common questions, we hope to provide clarity and promote safe use. If you have more concerns or need further assistance, consult with your healthcare provider for personalized advice.

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This article, authored and reviewed by Clare Waismann, M-RAS, SUDCC II, Founder of Waismann Method Advanced Treatment for Opiate Dependence, is for informational purposes only and should not be considered medical advice or a recommendation. Consult a healthcare professional for guidance and treatment options. While we strive to maintain high editorial standards, please be aware that information may become outdated. Waismann Method, its employees, agents, and associated individuals are not liable for any errors, omissions, or consequences resulting from the use of the information provided.